Corynebacterium diphtheriae and Related Toxigenic Species: Genomics, Pathogenici

Description: Corynebacterium diphtheriae and Related Toxigenic Species by Andreas Burkovski Corynebacterium diphtheriae is the classical etiological agent of diphtheria and the type strain of the genus Corynebacterium. FORMAT Hardcover LANGUAGE English CONDITION Brand New Publisher Description Corynebacterium diphtheriae is the classical etiological agent of diphtheria and the type strain of the genus Corynebacterium. While diphtheria of the respiratory tract became rare with the introduction of vaccination programs in industrialized countries, even today several thousand cases per year are reported to the World Health Organization. This shows that diphtheria is not completely eradicated and that reservoirs exist. The book summarizes the latest advances made in understanding C. diphtheriae and the closely related species Corynebacterium ulcerans and Corynebacterium pseudotuberculosis. Topics addressed are genomics of toxigenic corynebacteria, host-pathogen-interaction, detection, surveillance and treatment as well as application aspects. Back Cover Corynebacterium diphtheriae is the classical etiological agent of diphtheria and the type strain of the genus Corynebacterium . While diphtheria of the respiratory tract became rare with the introduction of vaccination programs in industrialized countries, even today several thousand cases per year are reported to the World Health Organization. This shows that diphtheria is not completely eradicated and that reservoirs exist. The book summarizes the latest advances made in understanding C. diphtheriae and the closely related species Corynebacterium ulcerans and Corynebacterium pseudotuberculosis . Topics addressed are genomics of toxigenic corynebacteria, host-pathogen-interaction, detection, surveillance and treatment as well as application aspects. Table of Contents Diphtheria and Its Etiological Agents.- Corynebacterium diphtheriae, Corynebacterium ulcerans and Corynebacterium pseudotuberculosis - General Aspects.- Comparative Genomics and Pathogenicity Islands of Corynebacterium diphtheriae, Corynebacterium ulcerans and Corynebacterium pseudotuberculosis.- Corynephages: Infections of the Infectors.- Toxin Structure, Delivery and Action.- Iron Acquisition and Iron-Dependent Gene expression in Corynebacterium diphtheria.- Assembly and Function of Corynebacterium diphtheria.- Toxigenic Corynebacteria: Adhesion, Invasion and Host Response.- Detection Methods for Laboratory Diagnosis of Diphtheria.- Diphtheria Surveillance.- History of diphtheria Vaccine Development.- Antimicrobial Susceptibility and Treatment.- Sialidases of Corynebacteria and Their Biotechnological Application.- Molecular Genetic Tools for Research in Corynebacterium diphtheria.- Diphtheria Toxin Based Molecules as Therapeutic Approaches. Review From the book reviews:"It extensively examines the genomics, pathogenicity, diagnosis, and treatment of these bacteria as well as vaccine development. … an excellent resource for graduate, postdoctoral fellows, and basic scientists in microbiology, molecular genetics, or public health. It also would be a useful introductory tool for infectious disease fellows who are interested in pursuing public health and/or basic science research as part of a physician/scientist training pathway." (Shirley F. Delair, Doodys Book Reviews, August, 2014) Review Quote From the book reviews: "It extensively examines the genomics, pathogenicity, diagnosis, and treatment of these bacteria as well as vaccine development. ... an excellent resource for graduate, postdoctoral fellows, and basic scientists in microbiology, molecular genetics, or public health. It also would be a useful introductory tool for infectious disease fellows who are interested in pursuing public health and/or basic science research as part of a physician/scientist training pathway." (Shirley F. Delair, Doodys Book Reviews, August, 2014) Feature Several Corynebacterium glutamicum books have been published, but little to nothing about C. diphtheriae A considerable number of research groups work on pili, surface structures, vaccines, distribution, host-pathogen-interactions, Fe metabolism, biotechnological applications (vectors systems to induce cell death, sialidase) Recently published genome sequences give the unique opportunity to compare C. diphtheriae genomes Details ISBN9400776233 Publisher Springer Year 2013 ISBN-10 9400776233 ISBN-13 9789400776234 Format Hardcover Imprint Springer Place of Publication Dordrecht Country of Publication Netherlands Edited by Andreas Burkovski DEWEY 614.5123 Short Title CORYNEBACTERIUM DIPHTHERIAE & Language English Media Book Pages 293 Edition 2014th Subtitle Genomics, Pathogenicity and Applications DOI 10.1007/978-94-007-7624-1 Publication Date 2013-11-18 Author Andreas Burkovski Edition Description 2014 ed. Alternative 9789402401929 Audience Professional & Vocational Illustrations 8 Illustrations, color; 14 Illustrations, black and white; XVII, 293 p. 22 illus., 8 illus. in color. We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:96309044;

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